Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Fédération de recherche en infectiologie de la région Centre-Val de Loire Région Centre Val de Loire

Home page

Cell and tissue analyses

Cell and tissue analyses
© Florence Carerras

Cellular and tissue analyses combine histology, imaging and cytometry activities.


Copyright : Christelle Rossignol


The PIXANIM platform (Phenotyping by In / eX vivo Imaging from Animal to Molecule) is an experimental and analytical platform. PIXANIM enables animal phenotyping and functional exploration, from the whole animal to the molecule. PIXANIM is ISO 9001 certified, IBISA labeled and member of the Institut Carnot France Futur Elevage. 2D / 3D in- / ex-vivo imaging with a set of technologies that can range from the whole animal to the molecule and can be combined with each other.

Equipment : IRM 3 Teslas, CT scan offering 128 sections, a Kratoscope, a doppler ultrasound station, a dual color endomicroscope and an image intensifier.      

Location : Nouzilly

Contact :,

Website and social networks :


Imaging and infectiology laboratory. Using imaging technologies, IMI contributes to the development of animal models of infectious diseases. 

Small animal imaging: fluorescence and bioluminescence analysis in vivo on anesthetized animal, ex vivo on organs, in vitro on cells (kinetics of cellular cooperation); experimental protocols for mice, poultry, which may involve class 2 or 3 pathogens; on-demand: development of methodological tools and study models.

Equipment : IVIS SpectrumTM 2D et 3D Optical Tomography System (PerkinElmer). Containments A2 L2, A3 L3.

Contact :


Copyright : Isabelle Lantier

Confocal microscope and light sheet: organ transparency either by Disco or Clarity techniques; organ immunostaining of the size equivalent to mouse organs.

Equipment : level 2 containment ; confocal microscope SP8, Leica, Lens : 20x, 25x,40x, 63x et 100x ; Diodes 405 nm, 561nm, Laser argon 458, 476, 488,

 496, 514 et HeNe 633 ; Thermostatic culture chamber / CO2 ; "DLS" suystem (Digital Light Sheet) adapted to the confocal microscope.

Contact :


Copyright : Christelle Rossignol

Histology: treatment of infectious or non-infectious animal tissues using conventional histology techniques (fixed tissues impregnated with paraffin, frozen tissues); making histological sections; classic colorings; on-demand tissue immunohistochemistry; readings and images taken under the microscope.

Equipment : level 2 containment ; TP1020 paraffin impregnation machine, LEICA; Inclusion table in paraffin TS99, MEDITE, Tech-Inter; Microtome RM2235, LEICA; Vibratome 1200S, LEICA; Cryomicrotome CM3050S, LEICA; Binocular magnifier C-PS-160, Nikon; Eclipse 80i NIKON microscope (fluorescence and brightfield).

Contact :


Copyright : Christelle Rossignol

Cytometry laboratory: Multi-fluorescence analysis and sorting.

Equipment : level 2 containment; MoFlo Astrios high speed cell sorter under PSM; 4 lasers and 12 fluorescences; Separation of 6 cell populations simultaneously, recovery in tubes (all formats) or microplates, cloning possible; Sorting speed up to 70,000 cells / second; Samples from 0.1 to 150 µm (bacteria, cells, parasites, etc.); Analyzer cytometer (LSR Fortessa) with 4 lasers and 12 fluorescences.

Contact :

Location : Nouzilly

Website :


Copyright Alix Sausset

PFME Ibisa

IBiSA Electron Microscopy Platform of Tours University. The Microscopy Department is a technical platform pooling microscopic imaging devices and skills to provide services to teams from Tours University, but also to large organizations outside the University and to the private industrial sector. This department is associated with several federative structures: PST Analysis of Biological Systems, Group of Scientific and Technical Means of Tours (GMSTT), FED 4225 (former IFR 136) and FED 4226 (former IFR 135). the platform is a member of the Network of Common Microscopy Centers (RCCM).

The platform was IBiSA labeled (Infrastructures in Biology, Health and Agronomy) in 2015.

All areas of microscopic exploration are covered: TEM analysis of cells and tissues and electron immunomicroscopy; TEM and SEM analysis of particles (bacteria, viruses, DNA, liposomes, macromolecules); Surface condition, elemental analysis and spectral mapping by SEM and EDS probe; 3D reconstruction from serial sections in MET; Localization of labeled cellular elements (viral proteins, signaling factors, etc.) by confocal laser scanning microscopy; 3D reconstruction of volumes and quantification of the colocalization of markers from confocal microscopy acquisitions; Time-lapse confocal acquisitions on living cells.

Equipment : transmission EM, scanning electron microscope, Confocal EM. JEOL JEM-1400 Plus Transmission Electronic Microscope (120 kV); JEOL JEM-1011 Transmission Electronic Microscope (100 kV); Zeiss ULTRA Plus Scanning Field Effect Electronic Microscope; High Resolution Confocal Laser Scanning Microscope.

Location : Tours

Contact :

Website :



Multidisciplinary technological platform of the GEIST research institute from Limoges University, bringing together the major families of technologies for the life sciences and allowing, within a single structure, the study of whole organisms, tissues, cells and molecules. BISCEm is organized into 3 activity poles which contribute to the advancement of the research programs of user teams with the following main research themes: infectious agents (bacteria, viruses, parasites), immunity, transplantation, cancer, neurosciences, and natural resources.

The cell and tissue analysis division of the platform combines the histology platforms (preparation of blocks, section, staining, immunological labeling, scan of slides), fluorescence micro- and macroscopy (full field or confocal, fixed or living material, analysis image) and flow cytometry (flow cytometry and imaging, cell sorting). The pole works in close collaboration with the pathology service of Limoges University Hospital Center and with CARMALIM and PLATINOM, 2 other platforms of the University which have complementary and / or, for some, innovative imaging tools for the life sciences. The cluster has set up training in imaging, with CARMALIM and PLATINOM.

Equipment : BISCEm has more than 80 equipment for basic care and the performance of experiments in respect of animal welfare, and more than 30 semi-heavy and heavy equipment and dedicated software for cell, tissue and molecular analyzes . The equipment is spread over nearly 1,300 m2 of dedicated premises on the Limoges university hospital campus. Other equipment is accessible via the 5 partner platforms and the site's research teams.

Location : Limoges

Contact :

Website :